Peptide Database

Peptide NameP5317-28

Function Ontology

Anticancer

Anticancer ▸ Antitumor

Antimicrobial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC70H105N15O20

DescriptionStandard

        QETFSDLWKLLP
    

Molecular Weight1476.67 Da

Isoelectric Point (pI)4.37

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.1031

GRAVY Index-0.35

Hydrophobic Moment 0.56

Boman Index0.09

Instability Index64.21

Aliphatic Index 97.50

Aromaticity 0.1667

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 574.59

LogP -2.55

H-bond Donors 19.0

H-bond Acceptors 19.0

Rotatable Bonds 46.0

Heavy Atoms 105.0

Ring Count 4.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0302488 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyE3 ubiquitin-protein ligase

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Anticancer Cytotoxic

TargetHCT-116-p53+/+

Activity30 μM

MethodIC50

RECORD: Rec_0395588 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]