Peptide Database

Peptide NameProgonadoliberin-3

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC333H514N104O99S2

DescriptionStandard

        QHWSYGWLPGGKRSVGELEATIRMMGTGGVVSLPEEASAQTQERPRPYNVIDDGSRHFHRKKRFPDN
    

Molecular Weight7622.41 Da

Isoelectric Point (pI)9.40

Net Charge (pH 7.0)2.03

Net Charge (pH 7.4) 1.66

Charge Density (pH 7.0) 0.0304

GRAVY Index-1.01

Hydrophobic Moment 0.82

Boman Index-0.19

Instability Index50.72

Aliphatic Index 50.90

Aromaticity 0.0896

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3285.10

LogP -36.25

H-bond Donors 115.0

H-bond Acceptors 106.0

Rotatable Bonds 248.0

Heavy Atoms 538.0

Ring Count 16.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0202936 VERIFIED: YES

Provenance & Taxonomy

OrganismVerasper moseri [Animal]

FamilyProgonadoliberin

Tax ID98923

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour