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MYP_063230
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Basic Information
Gramicidin S 12, GS12
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
12 amino acids
C74H122N16O15
Standard
Sequence
VKLKYPKVKLYP
Physicochemical Analysis
1475.86 Da
10.00
3.73
3.51
0.3107
-0.45
0.12
-0.08
-3.37
113.33
0.1667
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
510.38
0.56
17.0
19.0
47.0
105.0
4.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0302266 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Enterobacter cloacae
256 μg/mL
MIC
PMID19278255;12712499 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19278255/
RECORD: Rec_0313328 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Salmonella typhimurium C610
15-50 μg/mL
MIC
PMID19278255;12712499 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19278255/
RECORD: Rec_0328084 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Streptococcus mitis
2 μg/mL
MIC
PMID19278255;12712499 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19278255/
RECORD: Rec_0364847 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630.0
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human erythrocytes
150 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/12712499/ PMID12712499 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12712499/
RECORD: Rec_0367015 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli DC2
15-50 μg/mL
MIC
PMID19278255;12712499 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19278255/
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