Peptide Database

Peptide NameMehamycin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length61 amino acids

Chemical FormulaC322H491N87O77S8

DescriptionStandard

        DVLSGKYKGPCYFGIIPCFVRGCKPKLFDAHRKLCIKLCKQEGFKSGHCSNFFKFQCWCTR
    

Molecular Weight7069.40 Da

Isoelectric Point (pI)9.41

Net Charge (pH 7.0)8.85

Net Charge (pH 7.4) 8.41

Charge Density (pH 7.0) 0.1451

GRAVY Index-0.19

Hydrophobic Moment 0.60

Boman Index-0.02

Instability Index2.78

Aliphatic Index 55.90

Aromaticity 0.1639

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2638.53

LogP -20.33

H-bond Donors 100.0

H-bond Acceptors 96.0

Rotatable Bonds 233.0

Heavy Atoms 494.0

Ring Count 16.0

Amide Bonds 63.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0001916 VERIFIED: YES

Provenance & Taxonomy

OrganismMeloidogyne hapla [Fungus]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetN. crassa CGMCC 3.1605 (CL 26.01 uM), G. candidum CCTCC AY 93038 (CL 35.05 uM), Candida albicans 2.4116(CL 29.64 uM), Gram+ Bacillus megaterium CGMCC 1.0459 (CL 8.97 uM), Bacillus subtilis CGMCC 1.2428 (CL 10.91 uM), Micrococcus luteus CGMCC 1.0290 (CL 8.67 uM), Penicillin-resistant Staphylococcus aureus P1383 (CL 8.07 uM), S. mutans ATCC 1.2499 (CL 8.45 uM), S. salivarius ATCC 1.2498 (CL 8.93 uM)