Peptide Database

Peptide NameHuman drosomycin-like defensin

Function Ontology

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Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC115H175N41O35S4

DescriptionStandard

        QKSWHEVGRPSPHCGPSRQCGCHMD
    

Molecular Weight2820.13 Da

Isoelectric Point (pI)7.99

Net Charge (pH 7.0)1.00

Net Charge (pH 7.4) 0.59

Charge Density (pH 7.0) 0.0399

GRAVY Index-1.29

Hydrophobic Moment 0.57

Boman Index-0.26

Instability Index81.80

Aliphatic Index 11.60

Aromaticity 0.0400

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1208.47

LogP -16.23

H-bond Donors 44.0

H-bond Acceptors 43.0

Rotatable Bonds 87.0

Heavy Atoms 195.0

Ring Count 8.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0038777 VERIFIED: YES

Provenance & Taxonomy

OrganismCapra hircus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)