Peptide Database

Peptide NamePyocin large subunit

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length511 amino acids

Chemical FormulaC2430H3791N679O758S17

DescriptionStandard

        MANKRVAVVGDRTTTGGVIITGADSFFGDGKPVARQGDYATCPKCNKVGTIIQGLNTFNIHGKGAALDGYLIACGCPTGTHRIIACHSMIFADDTPQPAPSVRASSVASGTSTPASLSQDIAPQSSQAIRSNTPTVVEPVFAKSCLRESGCTDAGTSAEPIDNFGQMAFYQATALAVSAGTRSVTPEAGAIAVRYLGGASSRLFTGRLFTAPNPVTVGLIGIFYSSGLNSGEQDYLDQKKLESLAAQGGSAPTRVRFQWVKDSATGKMTVKGYHTDSGEVPVKMMRFNASSGFYEFWEAGAQGPTILWTPDNPGFIAPENTGNDDVFRPPPTITVLPEPTATGGYTETLPIPEEKNFRDYILVHPTGAFQPVYIYLSKPPVKLLEVELYGDFEGRSRGGEYNADHMPSAAAVRAYLKRKYPDADDNDLREMAKNVASIVVPIDVHRKISQTYGGRNSSAQIEEDSHELKSAMDRNFNAIKQVLKDDYGVTETELEQAREKMHRLNREQRWY
    

Molecular Weight55190.29 Da

Isoelectric Point (pI)6.05

Net Charge (pH 7.0)-4.72

Net Charge (pH 7.4) -5.62

Charge Density (pH 7.0) -0.0092

GRAVY Index-0.36

Hydrophobic Moment 0.68

Boman Index0.01

Instability Index45.61

Aliphatic Index 70.49

Aromaticity 0.0841

Extinction Coeff. Reduced 50310.00

Extinction Coeff. Oxidized 50685.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0296047 VERIFIED: YES

Provenance & Taxonomy

OrganismPragia fontium [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)