Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length452 amino acids

Chemical FormulaC2234H3568N616O618S15

DescriptionStandard

        TNPGFVVRITQAGLDYANRHATAVLEKELARLKLPDISGDFRIRLLGKVHYEISGLNLRNFHLPHSQISTVPNVGLQASISNAFAELDGRWRVKLRFIRHHGSFRLKVEDISIKISLKLGRDTSGKPTIEPSSCSTHISRVRVRFSGSFGWLYNLFHKAIESKLRKTLESKVYALGSAVPSPSRSSSAPCLAVTAKIDAMTGIDYSLVAPPVATAQSLNVDLKGECFSLAHRTAVPFAPPVLAFPADQDRMIYFGASSYFFNTAGFAYHATGALVFEITDSMVRKGGGMGPAASRLSEFLCTTLDKLYPNMLMKLRLSAPSAPFLSIGTNGLSLRPVVDIQAYAILSDASLAPLFLLNLVSDVFATINLKSGRIAGRLDMGRLKLFSFPLSLHPQVKMLQSIMNIFASSILLPRLNERLDKGFPLPLLDRIQLSNILMQFHQVSGGARACPA
    

Molecular Weight49424.96 Da

Isoelectric Point (pI)9.93

Net Charge (pH 7.0)20.42

Net Charge (pH 7.4) 19.47

Charge Density (pH 7.0) 0.0452

GRAVY Index0.13

Hydrophobic Moment 0.70

Boman Index0.10

Instability Index44.70

Aliphatic Index 101.04

Aromaticity 0.0841

Extinction Coeff. Reduced 25900.00

Extinction Coeff. Oxidized 26150.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0338012 VERIFIED: NO

Provenance & Taxonomy

OrganismChauna torquata [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria