Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length363 amino acids

Chemical FormulaC1844H2893N457O503S14

DescriptionStandard

        LLKQKAASYRVSQMMAVWIQNKLKSTEIPEVRGGVDIGIGTVEYVISNMQVVQCSMSGPSMEFVNGIGVSVEVSQLSLAITGSWATQFGIIHDGGSVDLAVYNIKIKTLLGLGDEAGRLSITTISCSDDVGGVHIQFHGGASFFFQPFVSAFQGQISEMIHVRVCHFFISKTDEPNQHLYLLLVIFLIVSHAIPKSFPIHLNTSQFGAFIPQLRTLYPNMEMQVLLYASKTPLFSFSSGVIDVHVPVAAKFSVVKPDGMLVPLFRLDVVSFVFGYIKLLTVRTDPLGIVLFIIIIILLCIVDYLKTGFLLPTLQDFSLINSKLLIKNGFVVIFTDVENSWTVSMKTKVQTSPNNHFNGVNLHA
    

Molecular Weight39961.36 Da

Isoelectric Point (pI)7.30

Net Charge (pH 7.0)0.70

Net Charge (pH 7.4) -0.18

Charge Density (pH 7.0) 0.0019

GRAVY Index0.51

Hydrophobic Moment 0.53

Boman Index0.27

Instability Index19.13

Aliphatic Index 114.24

Aromaticity 0.1019

Extinction Coeff. Reduced 28420.00

Extinction Coeff. Oxidized 28670.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0308104 VERIFIED: NO

Provenance & Taxonomy

OrganismSinocyclocheilus anshuiensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria