Peptide Database

Peptide Nameneuromedin B (1-30) (human)

Function Ontology

Neurological / Signaling ▸ Neuropeptide activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC156H242N50O41S

DescriptionStandard

        LSWDLPEPRSRASKIRVHSRGNLWATGHFM
    

Molecular Weight3505.97 Da

Isoelectric Point (pI)11.54

Net Charge (pH 7.0)2.94

Net Charge (pH 7.4) 2.63

Charge Density (pH 7.0) 0.0979

GRAVY Index-0.67

Hydrophobic Moment 0.37

Boman Index-0.14

Instability Index41.38

Aliphatic Index 68.33

Aromaticity 0.1000

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1471.04

LogP -14.26

H-bond Donors 54.0

H-bond Acceptors 47.0

Rotatable Bonds 111.0

Heavy Atoms 248.0

Ring Count 9.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0106849 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor agonist Neuropeptide activity Signaling peptide

TargetBB1 receptor (Human); BB2 receptor (Human)

Activity0.198-0.304 nM

MethodIC50