Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length567 amino acids

Chemical FormulaC2731H4318N782O860S19

DescriptionStandard

        MGAMGFYLRVRDPTTCGGKILTGDETLSWYGVAGAREGDSVSCGQHPGTYRILGGTSDTWDEGRRLAGTLDSVSSCPCRARFIQTIPDCYIKDDTPEEQAEKARLLALATLREKQEQQEAEEKQLVEERDRNRVFAKSCLRGEGCNDAGEEQEPHTNFAAMAFYQAVPPADPASDTDVPQHAQTAKKKKPVDDIPKPKKRSALYKWLNGDHEEIEYQRATAAATSAANAQMAVEGASVLGLVGGNAITSGTWAVKLGEMATGIGRIAASGPGAPIAAVVLGMMPGRLNDGEQDFIDRMRLEQMREAPSRVRYTWEQDDKGNPVPHGWHTPPGKDMVRVRKMEWDSSRKAYTFTTEEDPRITIIWTPDSSGVNVPSNTGNQNPVRIPNPVVVDPLPEDTSIEATTTPAPEEKNFADYILILPLPNIPPIYVYLSKPPVEFLEVDLYSNLEGRSREGKYHADHIPSKAAVKEYYRNLDPLLDKDDINDLANEVAAIIVPIDAHRKISETYGRRNSETQIKLDASNLRAAVDRNLDAIKPALKEHGATEAQIEAARIKMHKFNSSVGLYK
    

Molecular Weight62475.46 Da

Isoelectric Point (pI)5.39

Net Charge (pH 7.0)-14.49

Net Charge (pH 7.4) -15.54

Charge Density (pH 7.0) -0.0256

GRAVY Index-0.59

Hydrophobic Moment 0.65

Boman Index-0.08

Instability Index40.87

Aliphatic Index 74.06

Aromaticity 0.0635

Extinction Coeff. Reduced 70820.00

Extinction Coeff. Oxidized 71195.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0060598 VERIFIED: YES

Provenance & Taxonomy

OrganismCitrobacter tructae [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)