Peptide Database

Peptide NameEndolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length158 amino acids

Chemical FormulaC778H1242N234O237S13

DescriptionStandard

        MTSTHVRTNKEGLEIIGNAEGCMRNPYVCPTGYLTVGIGSRIYSDEPAVRREGLTDQEIADRWVKNIQEAEKCVNDWFHGKDMNTNQFSAMTSMVFNHGCTRLRKNKDGSPTKIYTAARKQNWTEMCNRITDWDMGGKYRGLTIRKQKEKALCLKPVQ
    

Molecular Weight18082.46 Da

Isoelectric Point (pI)9.18

Net Charge (pH 7.0)6.72

Net Charge (pH 7.4) 6.22

Charge Density (pH 7.0) 0.0425

GRAVY Index-0.78

Hydrophobic Moment 0.75

Boman Index-0.17

Instability Index32.05

Aliphatic Index 59.24

Aromaticity 0.0759

Extinction Coeff. Reduced 29450.00

Extinction Coeff. Oxidized 29825.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7728.01

LogP -85.70

H-bond Donors 276.0

H-bond Acceptors 260.0

Rotatable Bonds 613.0

Heavy Atoms 1262.0

Ring Count 24.0

Amide Bonds 174.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0329361 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage JEP7 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic