Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length220 amino acids

Chemical FormulaC1102H1673N249O341S9

DescriptionStandard

        VDDLVEVDYSLSSLPAVFQPFIDLDLKGTVFPAGNYSGSPYMVAPFTVTDHSDSMLYLAFSEYFFQTSSFAYYTAGAFNTTIAEETCSYFNISTEIFGSIIPEVAKYSVTPYPVMLTLMATEIPVISLEQDSFTVEIQGSMEVLAVLPDSTTQSLFTMNVAANSSISLNIFDQKLMGSLCLNRLQFSLAHSNVGFFEISLLENILSYVLQTEVIPSANGK
    

Molecular Weight24154.12 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-18.08

Net Charge (pH 7.4) -18.47

Charge Density (pH 7.0) -0.0822

GRAVY Index0.36

Hydrophobic Moment 0.55

Boman Index0.26

Instability Index47.19

Aliphatic Index 96.14

Aromaticity 0.1273

Extinction Coeff. Reduced 16390.00

Extinction Coeff. Oxidized 16515.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0015195 VERIFIED: NO

Provenance & Taxonomy

OrganismOxyruncus cristatus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria