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MYP_062994
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Basic Information
T20v2(T20 [L8I; Q13,15R; E22A])
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition
Standard
36 amino acids
C202H304N54O60
Standard
Sequence
YTSLIHSIIEESRNRQEKNEQALLELDKWASLWNWF
Physicochemical Analysis
4448.90 Da
5.06
-2.14
-2.41
-0.0595
-0.76
0.53
-0.09
62.82
92.22
0.1389
17990.00
17990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1894.34
-14.81
66.0
59.0
149.0
316.0
9.0
40.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0233991 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HIV-1 JRCSF
PMID31228294 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31228294/
RECORD: Rec_0288745 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Antiviral
HIV-1 JRCSF; U87 cells
0.06 μg/mL
IC50
PaperPubMed PMID: 31228294 PMID31228294 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31228294/
RECORD: Rec_0332862 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Antiviral
HIV-1 92BR020:inhibition of pseudovirus infection in U87 cells
0.17 μg/mL
IC50
PaperPubMed PMID: 31228294 PMID31228294 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31228294/
RECORD: Rec_0355819 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Antiviral
HIV-1 IAVI C22:inhibition of pseudovirus infection in U87 cells
0.09 μg/mL
IC50
PaperPubMed PMID: 31228294 PMID31228294 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31228294/
RECORD: Rec_0361500 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Antiviral
HIV-1 N43; U87 cells
0.06 μg/mL
IC50
PaperPubMed PMID: 31228294 PMID31228294 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31228294/
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