Peptide Database

Peptide NamePeptide 33

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC105H186N40O20

DescriptionStandard

        RPKKPRPKLPRPRPPRPVR
    

Molecular Weight2328.86 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)8.76

Net Charge (pH 7.4) 8.55

Charge Density (pH 7.0) 0.4609

GRAVY Index-2.29

Hydrophobic Moment 0.42

Boman Index-0.87

Instability Index66.26

Aliphatic Index 35.79

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 966.26

LogP -8.16

H-bond Donors 33.0

H-bond Acceptors 29.0

Rotatable Bonds 68.0

Heavy Atoms 165.0

Ring Count 8.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0273851 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-Term1-Amino cyclohexyl carboxylic acid

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli BW25113

Activity16-32 μg/mL

MethodMIC

RECORD: Rec_0411943 VERIFIED: YES