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MYP_062986
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Basic Information
Metalnikowin-1 (Metalnikowin I; Insects, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
15 amino acids
C80H128N26O22S
Standard
Sequence
VDKPDYRPRPRPPNM
Physicochemical Analysis
1838.10 Da
9.98
1.73
1.52
0.1156
-2.07
0.23
-0.61
13.63
19.33
0.0667
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
776.41
-7.18
25.0
25.0
52.0
129.0
6.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0211838 VERIFIED: YES
Provenance & Taxonomy
Palomena prasina [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Salmonella typhimurium
50-100 μM
MIC
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP03312
RECORD: Rec_0213806 VERIFIED: YES
Provenance & Taxonomy
Palomena prasina [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli D22
50-100 μM
MIC
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP03312
RECORD: Rec_0219469 VERIFIED: YES
Provenance & Taxonomy
Palomena prasina [Animal]
Metalnikowin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
PaperJ. Insect Physiol. 1996; 42: 81-89 | http://www.sciencedirect.com/science/article/pii/0022191095000852
RECORD: Rec_0241207 VERIFIED: YES
Provenance & Taxonomy
Palomena prasina [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Non-hemolytic
Gram-negative bacteria
Evidence URLhttps://www.rcsb.org/structure/5HCP
RECORD: Rec_0244805 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 46.7%, C 53.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antiviral Antimicrobial Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
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