Peptide Database

Peptide NameNK23b

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC118H222N38O29S

DescriptionStandard

        KILRGVSKKIMRRISKDILTGKK
    

Molecular Weight2669.33 Da

Isoelectric Point (pI)11.76

Net Charge (pH 7.0)7.76

Net Charge (pH 7.4) 7.54

Charge Density (pH 7.0) 0.3372

GRAVY Index-0.51

Hydrophobic Moment 0.91

Boman Index-0.33

Instability Index37.86

Aliphatic Index 114.35

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1143.33

LogP -9.58

H-bond Donors 43.0

H-bond Acceptors 38.0

Rotatable Bonds 102.0

Heavy Atoms 186.0

Ring Count 0.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0423924 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic

TargetHuman erythrocytes: <5% Hemolysis=100 μg/ml

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