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MYP_062949
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Basic Information
Venom antimicrobial peptide-9
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Insecticidal/Pest control ▸ Insecticidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
18 amino acids
C106H159N23O22
Standard
Sequence
FFGHLFKLATKIIPSLFQ
Physicochemical Analysis
2107.54 Da
10.00
1.85
1.59
0.1025
0.86
0.61
0.41
0.76
113.89
0.2222
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
713.50
-1.14
24.0
25.0
67.0
151.0
6.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0366822 VERIFIED: YES
Provenance & Taxonomy
Mesobuthus eupeus [Animal]
Meucin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0368710 VERIFIED: YES
Provenance & Taxonomy
Mesobuthus eupeus [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
S. oneidensis
PMID19088182;29896190 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19088182/
RECORD: Rec_0379165 VERIFIED: YES
Provenance & Taxonomy
Mesobuthus eupeus [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis AB208187
3.0 μM
MIC
PMID19088182;29896190 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19088182/
RECORD: Rec_0389876 VERIFIED: YES
Provenance & Taxonomy
Mesobuthus eupeus [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
penicillin-resistant Staphylococcus aureus
3.0 μM
MIC
PMID19088182;29896190 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19088182/
RECORD: Rec_0399029 VERIFIED: YES
Provenance & Taxonomy
Mesobuthus eupeus [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Micrococcus luteus
PMID19088182;29896190 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19088182/
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