Peptide Database

Peptide NameHepcidin antimicrobial peptide 2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC446H729N139O135S14

DescriptionStandard

        MKTFSVAVAVAVVLTFICLQESSADSVTEVQELEEPMSIGSPVAAYEEMPEESWKMPYASRSSSDRRRRRWRCRTCCRCCPRMKGCGICCRRR
    

Molecular Weight10647.32 Da

Isoelectric Point (pI)8.84

Net Charge (pH 7.0)4.43

Net Charge (pH 7.4) 4.06

Charge Density (pH 7.0) 0.0477

GRAVY Index-0.35

Hydrophobic Moment 0.70

Boman Index-0.18

Instability Index123.32

Aliphatic Index 57.63

Aromaticity 0.0645

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4451.30

LogP -50.44

H-bond Donors 172.0

H-bond Acceptors 154.0

Rotatable Bonds 352.0

Heavy Atoms 734.0

Ring Count 13.0

Amide Bonds 94.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0322211 VERIFIED: YES

Provenance & Taxonomy

OrganismPagrus auriga [Animal]

FamilyHepcidin

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0419321 VERIFIED: NO