Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length442 amino acids

Chemical FormulaC2240H3510N592O625S9

DescriptionStandard

        TNPGFVVRITQSGLDYAHQQGITILEKELAQLKLPDISGDFRIRHVGKVHYEISRLDLRSFHLPYSRISLVPNVGLQVSISNAFAEVDGNWRVKIYFIRDHGSFDLKVENVYIKINLKLGSDASGKPTIDTSDCSTRISKVRVHFWGKFGWLYNLFYGAVESRFRNILESKVCENVVTSVRSELQPYLQTLPVTARIDDKAGIDYSLVAPPTATAQTLDVDLKGEFFSLAHRSTVPFPPLALAFPPDHDRMVYFGASSYFFNTAGFAYHAAGALVFEITDSVIPKGTGFHLNTSTFSAFIPQLEKMYPDMPMKLRLSAPSAPFLNIGPGGLLLKPVVDIQAYAILPSSSLAPLFLLSLTSNVSAVIDVKSGHIVGSLTMGRLRLSLKHSDVGTFQVRMLQSLMNTIASTVLLPRLNERLAEGFPLPLPDRIQLSNILVRFHQ
    

Molecular Weight49022.01 Da

Isoelectric Point (pI)9.12

Net Charge (pH 7.0)6.54

Net Charge (pH 7.4) 5.58

Charge Density (pH 7.0) 0.0148

GRAVY Index0.09

Hydrophobic Moment 0.69

Boman Index0.12

Instability Index35.89

Aliphatic Index 101.88

Aromaticity 0.0995

Extinction Coeff. Reduced 37360.00

Extinction Coeff. Oxidized 37485.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0198994 VERIFIED: NO

Provenance & Taxonomy

OrganismCircaetus pectoralis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria