MYP_062920
Eval418
Anticancer
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Cytotoxic anticancer activity
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Cytotoxic
Antimicrobial
Antiviral
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Anti-Herpesvirus
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Antiviral
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Antiviral mechanism
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Toxicity / Safety
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Blood cell toxicity
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Hemolysis
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Hemolytic
Toxicity / Safety
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Cytotoxicity
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Cytotoxic
Venom / Toxin
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General toxin
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Cytotoxic
Standard
13 amino acids
C74H113N17O18
Standard
LWGEIWNTVKGLI
1528.79 Da
6.00
-0.24
-0.44
-0.0183
0.51
0.47
0.42
22.70
142.31
0.1538
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
570.74
-0.98
20.0
18.0
48.0
109.0
4.0
13.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0020883
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Cytotoxic
the cell viability of the peptide-treated Vero cells was greater than 95% after treatment with Eval418 at 10 μg/mL
RECORD: Rec_0025864
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
inhibition of viral entry in Vero cells
31.71 μg/mL
IC50
RECORD: Rec_0055788
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Cytotoxic
RECORD: Rec_0070481
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Hemolytic
The hemolysis rate of human erythrocytes was less than 50% when the concentration of Eval418 was as high as 200 μg/mL
RECORD: Rec_0072985
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
inhibition of viral attachment in Vero cells
3.7 μg/mL
IC50
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