Peptide Database

Peptide NameColicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length583 amino acids

Chemical FormulaC2686H4255N813O853S9

DescriptionStandard

        MSGGDGIGHNSGAHSTGGVNGSSSGRGGSSSGGGNNPNSGPGWGTTHTPDGHDIHNYNPGEFGGGGHKPGGNGGNHSGGTGDGQPPGAAMAFGFPALVPAGAGGLAVTVSGDALAAAIADVLAVLKGPFKFGAWGIALYGILPTEIAKDDPRMMSKIVTSLPADAVTESPVSSLPLDQATVSVTKRVTDVVKDERQHIAVVAGGPASIPVVDAKPTTHPGVFSVSAPGLPDLQVSTVKNAPATTALPRGITDEKDRTVHPAGFTFGGSSHEAVIRFPKESGQAPVYVSVTDVLTPEQVKQRQDEENRRQQEWDATHPVEVAERNYRLASDELNRANVDVAGKQERQIQAAQAVAARKGELDAANKTFADAKEEIKKFERFAHDPMAGGHRMWQMAGLKAQRAQNEVNQKQAEFNAAEKEKADADAALNVALESRKQKEQKAKDASDKLDKENKRNHPGKATGKGQPVGDKWLEDAGKEAGAPVPDRIADKLRDKEFKNFDDFRKKFWEEVSKDPELSKQFIPGNKKRMSQGLAPRARNKDTVGGRRSFELHHDKPISQDGGVYDMDNIRVTTPKLHIDIHRGK
    

Molecular Weight61873.04 Da

Isoelectric Point (pI)7.36

Net Charge (pH 7.0)1.25

Net Charge (pH 7.4) -0.09

Charge Density (pH 7.0) 0.0021

GRAVY Index-0.70

Hydrophobic Moment 0.75

Boman Index-0.09

Instability Index38.65

Aliphatic Index 63.16

Aromaticity 0.0515

Extinction Coeff. Reduced 40450.00

Extinction Coeff. Oxidized 40450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0018609 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Endonuclease Nuclease Non-hemolytic Non-ribosomal

TargetEscherichia coli