Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length201 amino acids

Chemical FormulaC1031H1549N231O308S9

DescriptionStandard

        QIDDLAEVDYSLNSLPAVFRPFIDLDLKGIVFPAGNYTDSPYVAASFAIPEQSDSMLYLAFSEYFFQTSSFAYYTAGAFNMTIAEEVKSGNSFVFFLFNFFLQTCSYFNINTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPVISLEQDSFTVEIQGSMEVLAVLPDSTTQSLFTMNIAANTSISLNIFDQKLMGSLCLNR
    

Molecular Weight22396.27 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-14.23

Net Charge (pH 7.4) -14.51

Charge Density (pH 7.0) -0.0708

GRAVY Index0.35

Hydrophobic Moment 0.60

Boman Index0.25

Instability Index44.19

Aliphatic Index 92.69

Aromaticity 0.1493

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0117999 VERIFIED: NO

Provenance & Taxonomy

OrganismClimacteris rufus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria