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MYP_062809
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Basic Information
M-PONTX-Nc3a
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Insecticidal/Pest control ▸ Insecticidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
30 amino acids
C154H243N43O42
Standard
Sequence
GWKDWLNKAKDFIKEKGPEILRAAANAAIN
Physicochemical Analysis
3368.84 Da
9.40
1.76
1.55
0.0588
-0.60
0.67
-0.06
42.67
85.00
0.1000
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1400.48
-10.52
47.0
44.0
114.0
239.0
6.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0012907 VERIFIED: YES
Provenance & Taxonomy
Neoponera commutata [Animal]
Ponericin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
>100 microM)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Bacillus subtilis
1.48-2.9 μM
MIC
PMID34302796 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34302796/
RECORD: Rec_0092992 VERIFIED: YES
Provenance & Taxonomy
Neoponera commutata [Animal]
Ponericin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
>100 microM)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Staphylococcus aureus
23.7-47.4 μM
MIC
PMID34302796 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34302796/
RECORD: Rec_0099705 VERIFIED: NO
Provenance & Taxonomy
Neoponera commutata [Animal]
Ponericin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperM-poneritoxin-Nc3a, M-PONTX-Nc3a (Poneratoxin) (Ponericin Nc3a) Evidence URLhttps://www.uniprot.org/uniprotkb/P0DV17/entry
RECORD: Rec_0114478 VERIFIED: YES
Provenance & Taxonomy
Neoponera commutata [Animal]
Ponericin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
>100 microM)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
2.3-4.7 μM
MIC
PMID34302796 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34302796/
RECORD: Rec_0341197 VERIFIED: YES
Provenance & Taxonomy
Neoponera commutata [Animal]
Ponericin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
>100 microM)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Acinetobacter baumannii
1.48 μM
MIC
PMID34302796 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34302796/
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