Peptide Database

Peptide NameNeutrophil antibiotic peptide NP-1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC454H726N138O146S8

DescriptionStandard

        MRTLALLIALLLLAFETQAETFQGTDEGVLDQEQLGADNQDMSISFGGDESTALQYADVRSRVTCYCRRGGCGSRESHIGYCRYRNTIYRLCCRR
    

Molecular Weight10709.98 Da

Isoelectric Point (pI)5.74

Net Charge (pH 7.0)-1.45

Net Charge (pH 7.4) -1.83

Charge Density (pH 7.0) -0.0153

GRAVY Index-0.32

Hydrophobic Moment 0.58

Boman Index-0.10

Instability Index46.46

Aliphatic Index 78.11

Aromaticity 0.0842

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7825.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4664.76

LogP -54.13

H-bond Donors 174.0

H-bond Acceptors 154.0

Rotatable Bonds 361.0

Heavy Atoms 746.0

Ring Count 9.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0120967 VERIFIED: NO

Provenance & Taxonomy

OrganismCricetulus griseus [Animal]

FamilyDefensin

Tax ID10029

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal