Peptide Database

Peptide NameCasein beta [058-072]

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC81H119N19O20

DescriptionStandard

        LVYPFPGPIHNSLPQ
    

Molecular Weight1678.93 Da

Isoelectric Point (pI)6.74

Net Charge (pH 7.0)-0.15

Net Charge (pH 7.4) -0.41

Charge Density (pH 7.0) -0.0102

GRAVY Index0.00

Hydrophobic Moment 0.35

Boman Index0.32

Instability Index87.91

Aliphatic Index 97.33

Aromaticity 0.1333

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 590.88

LogP -3.07

H-bond Donors 17.0

H-bond Acceptors 21.0

Rotatable Bonds 44.0

Heavy Atoms 120.0

Ring Count 7.0

Amide Bonds 16.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0107165 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyCasein-derived peptide

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory ACE inhibitory

TargetAngiotensin-I converting enzyme

Activity18 μM

MethodIC50

RECORD: Rec_0423696 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

Tax ID9913

Structure & Mods

Configproteolytic peptide fragment [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antihypertensive ACE inhibitory

TargetAngiotensin-converting enzyme (ACE)

MethodACE inhibition assay