Peptide Database

Peptide NameU1-sicaritoxin-Lg1a

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC70H109N19O30

DescriptionStandard

        VGTDFSGNDDISDVQK
    

Molecular Weight1696.72 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-3.26

Net Charge (pH 7.4) -3.48

Charge Density (pH 7.0) -0.2039

GRAVY Index-0.77

Hydrophobic Moment 0.47

Boman Index-0.09

Instability Index-11.26

Aliphatic Index 60.62

Aromaticity 0.0625

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 821.91

LogP -11.93

H-bond Donors 27.0

H-bond Acceptors 27.0

Rotatable Bonds 57.0

Heavy Atoms 119.0

Ring Count 1.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0374166 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Anticancer

RECORD: Rec_0405907 VERIFIED: YES

Provenance & Taxonomy

OrganismLoxosceles gaucho [Animal]

FamilyPonericin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-negative

TargetEnterobacter cloacae -12

Activity2.3 μM

MethodMIC

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