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MYP_062753
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Basic Information
U1-sicaritoxin-Lg1a
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
16 amino acids
C70H109N19O30
Standard
Sequence
VGTDFSGNDDISDVQK
Physicochemical Analysis
1696.72 Da
4.05
-3.26
-3.48
-0.2039
-0.77
0.47
-0.09
-11.26
60.62
0.0625
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
821.91
-11.93
27.0
27.0
57.0
119.0
1.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0002967 VERIFIED: YES
Provenance & Taxonomy
Loxosceles gaucho [Animal]
Ponericin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-negative
Escherichia coli D31
4.6 μM
MIC
PMID30563217 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30563217/
RECORD: Rec_0037344 VERIFIED: YES
Provenance & Taxonomy
Loxosceles gaucho [Animal]
Ponericin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-negative
Escherichia coli SBS363
4.6 μM
MIC
PMID30563217 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30563217/
RECORD: Rec_0038665 VERIFIED: YES
Provenance & Taxonomy
Loxosceles gaucho [Animal]
Ponericin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-negative
Pseudomonas aeruginosa PA14
4.6 μM
MIC
PMID30563217 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30563217/
RECORD: Rec_0056007 VERIFIED: YES
Provenance & Taxonomy
Loxosceles gaucho [Animal]
Ponericin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
1.15 μM
MIC
PMID30563217 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30563217/
RECORD: Rec_0120474 VERIFIED: YES
Provenance & Taxonomy
Loxosceles gaucho [Animal]
Ponericin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human RBC
137 μM
Hemolysis
PMID30563217 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30563217/
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