Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length484 amino acids

Chemical FormulaC2396H3768N620O677S16

DescriptionStandard

        MHSRMPEGSSPSRLPLLTWLCCLALCSEGANPGFVGRITEKGLDYARQEGVTVLQQELAKLKLPDFSGSFHVKVLGNVDYNFYGLNIGTFQLPSSSIAPLPGVGLKVSITNAVAALTGQWRVKKRRWFDHGSFDLKVEGISISVGLKLGTDGTGRLTAATSDCGAHISDVNIHISGRLGWLYNLFHRNIESGLRKAMEGKICETVTSAVSSKLMPFLQTLPVTAKIDNIAGIDYSLTGPPVTTNNSVDLALQGEFFSMTHRSPAPFPPPALSFPVDHDRMLYFGVSTYFFNTASNVYFNAGVMTFDITDSMIPKEFKLRLNTTTLGAFIPQLEKMFPNMLMVLKVSPSSAPLLRIAPESLSLTPVVNVQAFAILPNSSLAPLFVIEARAPVSAKVGVNSTRIVGSLKLGRLQLSLKHSDVGPFSVQLLQAILSYSASSILLPQINAWLADGFPLPLLDHVELYSLILQPYQDFLLFGADAQYKP
    

Molecular Weight52604.33 Da

Isoelectric Point (pI)8.66

Net Charge (pH 7.0)4.35

Net Charge (pH 7.4) 3.47

Charge Density (pH 7.0) 0.0090

GRAVY Index0.19

Hydrophobic Moment 0.81

Boman Index0.17

Instability Index48.30

Aliphatic Index 100.72

Aromaticity 0.0909

Extinction Coeff. Reduced 45380.00

Extinction Coeff. Oxidized 45630.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0164924 VERIFIED: NO

Provenance & Taxonomy

OrganismPogona vitticeps [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria