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MYP_062696
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Basic Information
mCRAMP-2 (mouse cathelin-related antimicrobial peptide 2; cathelicidin; Rodents, mammals, animals
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
38 amino acids
C197H338N56O50
Standard
Sequence
ISRLAGLLRKGGEKIGEKLKKIGQKIKNFFQKLVPQPE
Physicochemical Analysis
4291.14 Da
10.46
6.77
6.54
0.1780
-0.58
0.76
-0.14
17.10
102.63
0.0526
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1758.89
-13.10
59.0
57.0
157.0
303.0
4.0
41.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0388260 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
S. marcescens ATCC 8100
4 μM
MIC
PaperIdentification of CRAMP, a cathelin-related antimicrobial peptide expressed in the embryonic and adult mouse.
RECORD: Rec_0389268 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Cathelicidin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus Cowan I
32 μM
MIC
PMID9148921;8706928 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9148921/
RECORD: Rec_0392837 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0398594 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Cathelicidin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
1 μM
MIC
PMID9148921 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9148921/
RECORD: Rec_0400623 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Cathelicidin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Cryptococcus neoformans
16 μM
MIC
PMID9148921;8706928 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9148921/
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