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MYP_062686
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Basic Information
BmKn-22
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
11 amino acids
C56H97N15O13
Standard
Sequence
FIGAIARLLSK
Physicochemical Analysis
1188.46 Da
11.00
1.76
1.55
0.1599
1.22
0.67
0.33
1.37
160.00
0.0909
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
462.47
-2.27
17.0
15.0
40.0
84.0
1.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0039994 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperA scorpion venom peptide derivative BmKn-22 with potent antibiofilm activity against Pseudomonas aeruginosa.
RECORD: Rec_0090568 VERIFIED: YES
Provenance & Taxonomy
Mesobuthus martensii [Animal]
Aurein
34649
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
M. abscessus ATCC19977
400 μg/mL
MIC
PMID34780520 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34780520/
RECORD: Rec_0194378 VERIFIED: YES
Provenance & Taxonomy
Scorpion venom [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
HSC-4
97 μg/mL
IC50
PaperPubMed PMID: 27780132 PMID27780132 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27780132/
RECORD: Rec_0331785 VERIFIED: YES
Provenance & Taxonomy
Scorpion venom [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 27780132 PMID27780132 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27780132/
RECORD: Rec_0367628 VERIFIED: YES
Provenance & Taxonomy
Scorpion venom [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 27780132 PMID27780132 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27780132/
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