Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length268 amino acids

Chemical FormulaC1337H2147N347O385S14

DescriptionStandard

        MVKICCSLLLLSLLSGQLNANPGLKVRITQKGLEYAKEVGLEILKQNMEKDHFPDLTGHEKFGLGNLKYNISRIHITAVEFPSASISLIPGTGIKLVIGNASLTIDMNWNIRTWMFKDSGRSTVYISKVFVTAIFSTPLDNTGHTSIALTSCRTTSGDIDIKLSGKSGFLHNFFIKYLKKPIHRSLVTNSCPNIRSGIQLIDEDLRSLNVLMPIDDLAEVDYSLNSLPAVFRPFIDLDLKVIACSAICQDCYGFLLLYDPLSKMNMTA
    

Molecular Weight29691.35 Da

Isoelectric Point (pI)8.41

Net Charge (pH 7.0)2.97

Net Charge (pH 7.4) 2.29

Charge Density (pH 7.0) 0.0111

GRAVY Index0.16

Hydrophobic Moment 0.77

Boman Index0.13

Instability Index31.70

Aliphatic Index 108.77

Aromaticity 0.0784

Extinction Coeff. Reduced 21430.00

Extinction Coeff. Oxidized 21805.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0363407 VERIFIED: NO

Provenance & Taxonomy

OrganismAccipiter nisus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria