Peptide Database

Peptide NameUnnamed

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC46H65N9O11

DescriptionStandard

        GITSWLPF
    

Molecular Weight920.06 Da

Isoelectric Point (pI)5.53

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0300

GRAVY Index0.84

Hydrophobic Moment 0.31

Boman Index0.60

Instability Index61.71

Aliphatic Index 97.50

Aromaticity 0.2500

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 314.48

LogP -0.64

H-bond Donors 11.0

H-bond Acceptors 11.0

Rotatable Bonds 24.0

Heavy Atoms 66.0

Ring Count 4.0

Amide Bonds 7.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0024265 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0075598 VERIFIED: YES

Provenance & Taxonomy

OrganismLeucoraja erinacea [Animal]

FamilyBradykinin

Tax ID7782

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Vasoactive Hormone

RECORD: Rec_0105494 VERIFIED: YES

Provenance & Taxonomy

OrganismLeucoraja erinacea [Animal]

FamilyBradykinin

Tax ID7782

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0236921 VERIFIED: YES

Provenance & Taxonomy

OrganismLeucoraja erinacea [Animal]

FamilyBradykinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Targetproduces a concentration-dependent constriction of the mesenteric artery

Activity4370 μM

MethodEC50