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MYP_062603
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Basic Information
Unnamed
Gastrointestinal bioactivity
Gastrointestinal bioactivity ▸ Gastrointestinal motility
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Cell-cell communication
Standard
22 amino acids
C120H188N34O35S
Standard
Sequence
FVPIFTYGELQRMQEKERNKGQ
Physicochemical Analysis
2699.05 Da
8.50
0.77
0.55
0.0348
-1.17
0.43
-0.26
43.67
48.64
0.1364
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1166.19
-10.29
39.0
37.0
93.0
190.0
4.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0025154 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/
RECORD: Rec_0136497 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Motilin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Gastrointestinal motility
Competitive Radioimmunoassay
Rat plasma (Intravenous), in vivo; 195.6 s
RECORD: Rec_0144915 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Motilin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Endocrine Myotropic Receptor modulation
Experimental: 3.3±1.0 minutes; /198 seconds; Mammalian: 1.1 hour; Yeast: 3 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Motilin (Homo sapiens): PMID 22286034 PMID22286034 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22286034/
RECORD: Rec_0199116 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Motilin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Gastrointestinal motility
GPR38 agonist activity
0.01-0.011 μM
EC50
Intravenouly injected in Sprague-Dawley rats, in vivo; 198 s
PMID22286034 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22286034/
RECORD: Rec_0254479 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Motilin
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Endocrine Myotropic Receptor modulation
Experimental: 3.3±1.0 minutes; /198 seconds; Mammalian: 1.1 hour; Yeast: 3 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Motilin (Sus scrofa): PMID 4706833##22286034 PMID4706833;22286034 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/4706833/
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