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MYP_062580
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Basic Information
Unnamed
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor
Standard
45 amino acids
C243H423N69O68S
Standard
Sequence
RMKQIEDKIEEIESKQKKIENEIARIKKLLQLTVWGIKQLQARIL
Physicochemical Analysis
5431.44 Da
9.78
3.77
3.54
0.0838
-0.63
0.66
-0.21
92.22
123.56
0.0222
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2313.47
-15.81
79.0
73.0
204.0
381.0
2.0
50.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0000164 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
PaperPatent US 7811577 B2 Evidence URLhttps://patents.google.com/patent/US7811577B2/en PatentUS 7811577 B2
RECORD: Rec_0127457 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Fusion inhibitor
Qualitative inhibition
PaperHighly potent synergistic combinations of human immunodeficiency virus (HIV) fusion inhibitors PatentUS7919101
RECORD: Rec_0142612 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HIV-1
PMID11572974 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11572974/
RECORD: Rec_0144331 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
HIV gp41 N-peptide fusion inhibitor
32630.0
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Acetylation
Amidation
Bio-Activity Profile
Antiviral Anti-HIV Fusion inhibitor
HIV
PaperCovalently stabilized chimeric coiled-coil HIV gp41 N-peptides with improved antiviral activity Evidence URLhttps://patents.google.com/patent/US7811577B2/en PatentUS 7811577 B2
RECORD: Rec_0175397 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 95.6%, E 0.0%, T 0.0%, C 4.4% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperHIPdb: a database of experimentally validated HIV inhibiting peptides PMID23359817 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23359817/
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