Peptide Database

Peptide NameColicin-E3 (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length632 amino acids

Chemical FormulaC3032H4878N868O953S6

DescriptionStandard

        MGKNNSGGYDGSNLGGHTTNHGNGWSTTSDNRGDIGHHTDNGSSKGEHAWSRGDGGSGSGSSSSRNNDQKTLNYTDTPGTPVTVYAGGDTLSLGLGATLFALSQLQKEALMALLTDVTVISGRVFGLLGLFYPSQIAPDPKVHIHVKDFDIDNPHVLVTLPAEQMTRVPVENIPEHTSIPAGIIAQAVIDELAKNRPVVLTPVKSTPVPVVRAQKTDKPDVYTAQVIPGMKPLRITVDNSKQVKPAAAQTGSLPVSKQYLSAPEEKDNISHHAVIDFGSDHVPLYISVTKQVTPEEATKQAEKARDAWVADNPAGVSLFLAEINTLIAEKEKLLAEKQQVLKSKQALLDKYNRASPFENSGQKYSEKKGPLKAEIDQITAEVSSLQKELEDAAGNKALNEKTLAEVKALEQALNQIQIPEEARKFLAVAEKELEVAGAVATEKEKQLANKRRILKITQAEFQAFLDKYKRAGPFARSGMRFSEKEREFNAVSNQLSTEIGQLEKALSDAMESRKKAEDKKKAAEDKVKAEQDKKRQGVKDKGHSYHPAPKTEEIKGLGELKPGKDKTPKQGGAGTRKRWLGDKGRKIYEWDYQHGEIEGYRASDGQHLGAFDPKTGNQLKPADPKRNIKKYL
    

Molecular Weight68930.80 Da

Isoelectric Point (pI)8.90

Net Charge (pH 7.0)7.99

Net Charge (pH 7.4) 6.73

Charge Density (pH 7.0) 0.0126

GRAVY Index-0.70

Hydrophobic Moment 0.74

Boman Index-0.10

Instability Index34.88

Aliphatic Index 75.84

Aromaticity 0.0538

Extinction Coeff. Reduced 49850.00

Extinction Coeff. Oxidized 49850.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0418105 VERIFIED: NO

Provenance & Taxonomy

OrganismMorganella morganii [Bacterium]

FamilyColicin/Bacteriocin

Tax ID582

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence