Peptide Database

Peptide Name[D-Trp12,Tyr34]PTH-(7-34) (bovine)

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Receptor modulation ▸ Antagonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC163H249N47O42S2

DescriptionStandard

        FMHNLYKHLSSMERVEWLRKKLQDVHNY
    

Molecular Weight3603.14 Da

Isoelectric Point (pI)9.40

Net Charge (pH 7.0)2.02

Net Charge (pH 7.4) 1.66

Charge Density (pH 7.0) 0.0723

GRAVY Index-0.94

Hydrophobic Moment 0.60

Boman Index-0.20

Instability Index75.30

Aliphatic Index 76.43

Aromaticity 0.1429

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1474.80

LogP -9.63

H-bond Donors 52.0

H-bond Acceptors 49.0

Rotatable Bonds 122.0

Heavy Atoms 254.0

Ring Count 8.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0145884 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Bio-Activity Profile

Function

Receptor antagonist Signaling peptide

TargetPTH1 receptor (Human); PTH2 receptor (Human)