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MYP_062571
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Basic Information
NDVHR2
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Standard
35 amino acids
C156H269N45O57
Standard
Sequence
LGNVNNSISNALDKLEESNSKLDKVNVKLTGTSAL
Physicochemical Analysis
3687.07 Da
6.21
-0.24
-0.45
-0.0067
-0.38
0.58
-0.05
1.88
108.57
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1706.15
-23.35
57.0
57.0
131.0
258.0
0.0
40.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0125926 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
HR2 fusion-inhibitory peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-MDV Entry inhibition
Marek's disease virus(MDV)
65.3±0.9 μM
IC50
Mammalian: 5.5 h; Yeast: 3 min; E. coli: 2 min
PaperIn vitro and in vivo broad antiviral activity of peptides homologous to fusion glycoproteins of Newcastle disease virus and Marek's disease virus. | Chi XJ, Wang XJ, Wang CY, Cui XJ, Wang XJ. | J Virol Methods. 2014 Apr;199:11-6. | DOI:10.1016/j.jviromet.2013.12.022 | PMID:24412629 PMID24412629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24412629/
RECORD: Rec_0144253 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Newcastle disease virus(NDV):inhibition of viral infection in chicken embryo fibroblasts
18.9±2.8 μM
IC50
PaperPubMed PMID: 24412629 PMID24412629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24412629/
RECORD: Rec_0184638 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
HR2 fusion-inhibitory peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-NDV Entry inhibition
Newcastle disease virus(NDV)
18.9±2.8 μM
IC50
Mammalian: 5.5 h; Yeast: 3 min; E. coli: 2 min
PaperIn vitro and in vivo broad antiviral activity of peptides homologous to fusion glycoproteins of Newcastle disease virus and Marek's disease virus. | Chi XJ, Wang XJ, Wang CY, Cui XJ, Wang XJ. | J Virol Methods. 2014 Apr;199:11-6. | DOI:10.1016/j.jviromet.2013.12.022 | PMID:24412629 PMID24412629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24412629/
RECORD: Rec_0273484 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 24412629 PMID24412629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24412629/
RECORD: Rec_0318734 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Marek's disease virus(MDV):inhibition of viral infection in chicken embryo fibroblasts
65.3±0.9 μM
IC50
PaperPubMed PMID: 24412629 PMID24412629 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24412629/