Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC390H628N104O112S5

DescriptionStandard

        MGLVLQGCLLLWSLRGALTQAAHAGITARVTQRALDYGVQAGMEMMEQIIKEKHIPDLKGSETLEFLKIDYVNYNFSK
    

Molecular Weight8726.11 Da

Isoelectric Point (pI)6.71

Net Charge (pH 7.0)-0.33

Net Charge (pH 7.4) -0.68

Charge Density (pH 7.0) -0.0042

GRAVY Index0.04

Hydrophobic Moment 0.68

Boman Index0.11

Instability Index15.06

Aliphatic Index 103.85

Aromaticity 0.0769

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 9970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3486.51

LogP -28.16

H-bond Donors 121.0

H-bond Acceptors 119.0

Rotatable Bonds 298.0

Heavy Atoms 611.0

Ring Count 10.0

Amide Bonds 84.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0225968 VERIFIED: NO

Provenance & Taxonomy

OrganismChinchilla lanigera (Long-tailed chinchilla) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria