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MYP_062487
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Basic Information
LyeTxI-b
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
24 amino acids
C129H219N33O29
Standard
Sequence
IWLTALKFLGKNLGKLAKQQLAKL
Physicochemical Analysis
2696.32 Da
10.60
4.76
4.54
0.1981
0.29
0.69
0.15
14.91
142.50
0.0833
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1028.01
-4.36
35.0
34.0
96.0
191.0
3.0
26.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0130110 VERIFIED: YES
Provenance & Taxonomy
Lycosa erythrognatha [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
Vero(African green monkey kidney)
100 μM
IC50
PaperPubMed PMID: 30449002 PMID30449002 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30449002/
RECORD: Rec_0143829 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
CH3CO
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
3.6
MIC
PMID30987317 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30987317/
RECORD: Rec_0168740 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
CH3CO
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
[Refer PubMed ID - 34169094: Acinetobacter baumannii [9] (
0.72
MIC
PMID30987317 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30987317/
RECORD: Rec_0174593 VERIFIED: YES
Provenance & Taxonomy
Lycosa erythrognatha [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
U-373MG ATCC
20.94±5.18 μM
IC50
PaperPubMed PMID: 30449002 PMID30449002 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30449002/
RECORD: Rec_0188326 VERIFIED: YES
Provenance & Taxonomy
Lycosa erythrognatha [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
SH-SY5Y
93.80±2.17 μM
IC50
PaperPubMed PMID: 30449002 PMID30449002 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30449002/
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