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MYP_062450
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Basic Information
HAL-1/6
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
12 amino acids
C65H107N17O14S
Standard
Sequence
GMWSKILGHLIK
Physicochemical Analysis
1382.72 Da
10.00
1.85
1.59
0.1538
0.42
0.57
0.31
11.07
130.00
0.0833
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
500.16
-1.13
18.0
18.0
47.0
97.0
3.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0018360 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Halictine
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antifungal
SW
>100 μM
IC50
PaperToxicity study of antimicrobial peptides from wild bee venom and their analogs toward mammalian normal and cancer cells PMID22100226 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22100226/
RECORD: Rec_0037631 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
HUVEC
40 μM
IC50
PaperToxicity study of antimicrobial peptides from wild bee venom and their analogs toward mammalian normal and cancer cells. Peptides. 2012 Jan;33(1):18-26. doi: 10.1016/j.peptides.2011.11.002. PMID: 22100226. PMID22100226 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22100226/
RECORD: Rec_0055448 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Antimicrobial Antifungal
PaperCancerPPD: a database of anticancer peptides and proteins PMID25270878 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25270878/
RECORD: Rec_0076368 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PaperToxicity study of antimicrobial peptides from wild bee venom and their analogs toward mammalian normal and cancer cells. Peptides. 2012 Jan;33(1):18-26. doi: 10.1016/j.peptides.2011.11.002. PMID: 22100226. PMID22100226 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22100226/
RECORD: Rec_0086623 VERIFIED: YES
Provenance & Taxonomy
Insecta [Animal]
50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperToxicity study of antimicrobial peptides from wild bee venom and their analogs toward mammalian normal and cancer cells PMID22100226 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22100226/
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