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MYP_062429
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Basic Information
Brevinin-1TSa
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
22 amino acids
C102H175N27O28
Standard
Sequence
FLGSIVGALASALPSLISKIRN
Physicochemical Analysis
2227.64 Da
11.00
1.76
1.55
0.0800
1.07
0.52
0.37
17.23
150.91
0.0455
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
877.56
-8.13
31.0
30.0
73.0
157.0
2.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0221671 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
12 μM
LD50
Paperhttps://pubmed.ncbi.nlm.nih.gov/16413829/ PMID16413829 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16413829/
RECORD: Rec_0234473 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
RECORD: Rec_0240900 VERIFIED: YES
Provenance & Taxonomy
Rana tsushimensis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis ATCC 29212
50 μM
MIC
PMID16413829 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16413829/
RECORD: Rec_0259001 VERIFIED: YES
Provenance & Taxonomy
Rana tsushimensis [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
PMID16413829 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16413829/
RECORD: Rec_0263510 VERIFIED: YES
Provenance & Taxonomy
Rana tsushimensis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
50 μM
MIC
PMID16413829 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16413829/
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