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MYP_062429
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Basic Information
Brevinin-1TSa
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
22 amino acids
C102H175N27O28
Standard
Sequence
FLGSIVGALASALPSLISKIRN
Physicochemical Analysis
2227.64 Da
11.00
1.76
1.55
0.0800
1.07
0.52
0.37
17.23
150.91
0.0455
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
877.56
-8.13
31.0
30.0
73.0
157.0
2.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0088504 VERIFIED: YES
Provenance & Taxonomy
Rana tsushimensis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Streptococcus group B HNTCC 80130
50 μM
MIC
PMID16413829 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16413829/
RECORD: Rec_0093423 VERIFIED: YES
Provenance & Taxonomy
Rana tsushimensis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Enterobacter cloacae HNTCC 5300
50 μM
MIC
PaperAntimicrobial peptides from the skin of the Tsushima brown frog Rana tsushimensis
RECORD: Rec_0104827 VERIFIED: YES
Provenance & Taxonomy
Rana tsushimensis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli ATCC 25922
25 μM
MIC
PaperAntimicrobial peptides from the skin of the Tsushima brown frog Rana tsushimensis
RECORD: Rec_0127495 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
RECORD: Rec_0137432 VERIFIED: YES
Provenance & Taxonomy
Rana tsushimensis [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Methicillin-resistant Staphylococcus aureus T7/20
25 μM
MIC
PMID16413829 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16413829/
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