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MYP_062409
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Basic Information
PolyP 3 (SAP)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
18 amino acids
C96H161N27O19
Standard
Sequence
VRLPPPVRLPPPVRLPPP
Physicochemical Analysis
1997.47 Da
12.00
2.73
2.52
0.1519
-0.22
0.41
-0.01
127.14
113.33
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
664.61
-1.91
19.0
22.0
47.0
142.0
9.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0031012 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID15054781 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15054781/
RECORD: Rec_0078459 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID15054781 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15054781/
RECORD: Rec_0097350 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus DSM 1104
122 μM
MIC
PMID22853904 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22853904/
RECORD: Rec_0128538 VERIFIED: YES
Provenance & Taxonomy
Zea mays [Plant]
Protein-derived CPP
4577
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
Fluorescein/FITC labeling
None
N-term detail: Labelled with fluoresceine; lowercase source residues at positions 1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18 denote stereochemical modification
Bio-Activity Profile
Cell-penetrating peptide
HeLa
Fluorescence-based uptake assay
PMID17635150 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17635150/
RECORD: Rec_0182272 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID15054781 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15054781/
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