Peptide Database

Peptide NamePA-4/PA-5

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length44 amino acids

Chemical FormulaC197H299N61O60S4

DescriptionStandard

        KYYGNGVTCGKHSCSVDWGKATTCIINNGALAWATGGHQGNHKC
    

Molecular Weight4610.11 Da

Isoelectric Point (pI)8.85

Net Charge (pH 7.0)2.98

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.0677

GRAVY Index-0.45

Hydrophobic Moment 0.47

Boman Index0.07

Instability Index-3.28

Aliphatic Index 48.86

Aromaticity 0.0909

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1950.91

LogP -25.95

H-bond Donors 72.0

H-bond Acceptors 70.0

Rotatable Bonds 148.0

Heavy Atoms 322.0

Ring Count 9.0

Amide Bonds 48.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0334601 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetNo disulfide bonds - L. ivanovii HPB28

Activity0.0019 μM

MethodMIC

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