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MYP_062355
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Basic Information
Caerin-3.1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Enzyme modulation ▸ Enzyme inhibition ▸ nNOS inhibitor
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
22 amino acids
C108H182N28O32
Standard
Sequence
GLWQKIKDKASELVSGIVEGVK
Physicochemical Analysis
2384.77 Da
8.43
0.76
0.55
0.0347
-0.10
0.56
0.06
8.46
115.00
0.0455
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
989.74
-7.66
34.0
33.0
85.0
168.0
2.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0384056 VERIFIED: YES
Provenance & Taxonomy
Litoria gilleni [Animal]
Caerin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
nNOS inhibitor
PaperR.J. Jackway et al. / Regulatory Peptides 151 (2008) 80-87. Disulfide-containing peptides from the glandular skin secretions of froglets of the genus Crinia: structure, activity and evolutionary trends Evidence URLhttps://www.uniprot.org/uniprotkb/P62563/entry
RECORD: Rec_0394727 VERIFIED: YES
Provenance & Taxonomy
Litoria splendida [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus epidermidis
>100 μg/mL
MIC
PaperPeptides from Australian frogs. Structures of the caerins and caeridin 1 from Litoria splendida
RECORD: Rec_0395411 VERIFIED: YES
Provenance & Taxonomy
Litoria splendida [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Bacillus cereus
>100 μg/mL
MIC
PaperPeptides from Australian frogs. Structures of the caerins and caeridin 1 from Litoria splendida
RECORD: Rec_0402981 VERIFIED: NO
Provenance & Taxonomy
Litoria splendida [Animal] [Animal]; Litoria gilleni [Animal] [Animal]; Litoria gracilenta [Animal] [Animal]; Litoria rothii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
RECORD: Rec_0405049 VERIFIED: NO
Provenance & Taxonomy
Litoria gilleni [Animal]
Caerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Evidence URLhttps://www.uniprot.org/uniprotkb/P62563/entry
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