‹ ›
MYP_062355
← PREVIOUS NEXT → BACK
Basic Information
Caerin-3.1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Enzyme modulation ▸ Enzyme inhibition ▸ nNOS inhibitor
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
22 amino acids
C108H182N28O32
Standard
Sequence
GLWQKIKDKASELVSGIVEGVK
Physicochemical Analysis
2384.77 Da
8.43
0.76
0.55
0.0347
-0.10
0.56
0.06
8.46
115.00
0.0455
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
989.74
-7.66
34.0
33.0
85.0
168.0
2.0
22.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0033985 VERIFIED: YES
Provenance & Taxonomy
Litoria rothii [Animal]
Caerin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
nNOS inhibitor
PaperR.J. Jackway et al. / Regulatory Peptides 151 (2008) 80-87. Disulfide-containing peptides from the glandular skin secretions of froglets of the genus Crinia: structure, activity and evolutionary trends Evidence URLhttps://www.uniprot.org/uniprotkb/P86505/entry
RECORD: Rec_0075732 VERIFIED: YES
Provenance & Taxonomy
Litoria splendida [Animal]
Caerin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
nNOS inhibitor
PaperR.J. Jackway et al. / Regulatory Peptides 151 (2008) 80-87. Disulfide-containing peptides from the glandular skin secretions of froglets of the genus Crinia: structure, activity and evolutionary trends Evidence URLhttps://www.uniprot.org/uniprotkb/P62562/entry
RECORD: Rec_0111284 VERIFIED: YES
Provenance & Taxonomy
Litoria rothii [Animal]
Caerin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PMID16124032;19539637 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16124032/
RECORD: Rec_0137574 VERIFIED: YES
Provenance & Taxonomy
Litoria rothii [Animal]
Frog skin active peptide (FSAP); Caerin subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Non-hemolytic
PMID16124032;19539637 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16124032/
RECORD: Rec_0142817 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
1 2 3 ... 6 NEXT LAST
Showing 5 records on this page · Page 1 of 6