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MYP_062338
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Basic Information
Cecropin A (1-7) + Melittine (2-9) [L4K][V14K]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
15 amino acids
C90H155N23O16
Standard
Sequence
KWKKFKKIGAVLKKL
Physicochemical Analysis
1815.34 Da
10.78
6.75
6.54
0.4502
-0.51
0.68
-0.19
-23.33
104.00
0.1333
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
668.65
-0.50
24.0
23.0
68.0
129.0
3.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0046481 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 6538P
16 μM
MIC
PMID18852279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18852279/
RECORD: Rec_0059433 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli BL21
01-2 μM
MIC
PMID18852279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18852279/
RECORD: Rec_0148632 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC BAA-41
16 μM
MIC
PMID18852279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18852279/
RECORD: Rec_0226288 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
3 % hemolysis at 64 μM
Hemolysis
PMID18852279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18852279/
RECORD: Rec_0235670 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus epidermidis
0.5 μM
MIC
PMID18852279 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18852279/
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