MYP_062256
Basic Information
Fusaricidin D
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antibacterial Anti-Gram-positive
Antimicrobial Antifungal
Standard
6 amino acids
C30H47N7O11
Standard
Sequence
TVYTQA
Physicochemical Analysis
681.73 Da
5.18
-0.60
-0.79
-0.1005
-0.03
0.31
0.17
-30.95
65.00
0.1667
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
312.60
-3.53
11.0
11.0
19.0
48.0
1.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0057507 VERIFIED: YES
Provenance & Taxonomy
Bacillus polymyxa [Bacterium]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Lipidation
Esterification
The carboxylic end of Ala6 forms an ester bond with the hydroxyl group of T1. Val2, Gln5, Ala6 are D-amino acids and Thr4 is a D-allo-Thr. In addition, the N-terminus NH is lipidated with 15-guanidino-3-hydroxypentadecanoic acid (GHPD). Refer to the article for additional physical properties
Bio-Activity Profile
Antimicrobial Antifungal
Inactive: Escherichia coli NIHJ, Klebsiella pneumoniae KC-1, Pseudomonas aeruginosa IFO 3445, S.marcescens IFO 3736, Candida albicans IFO 1594, S.cerevisiae HUT 7099
>100 μg/mL
MIC
RECORD: Rec_0077502 VERIFIED: YES
Provenance & Taxonomy
Paenibacillus polymyxa [Bacterium]; Bacteria [Bacterium]
1405; 2
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0266617 VERIFIED: YES
Provenance & Taxonomy
Bacillus polymyxa [Bacterium]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Lipidation
Esterification
The carboxylic end of Ala6 forms an ester bond with the hydroxyl group of T1. Val2, Gln5, Ala6 are D-amino acids and Thr4 is a D-allo-Thr. In addition, the N-terminus NH is lipidated with 15-guanidino-3-hydroxypentadecanoic acid (GHPD). Refer to the article for additional physical properties
Bio-Activity Profile
Antimicrobial Antifungal
Gram-positive Staphylococcus aureus FDA 209p, Staphylococcus aureus Smith, Micrococcus luteus IFO 3333, Bacillus subtilis ATCC 6633
<0.78-3.12 μg/mL
MIC
RECORD: Rec_0319794 VERIFIED: YES
Provenance & Taxonomy
Bacillus polymyxa [Bacterium]
Bacteriocin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal
Gram-positive
RECORD: Rec_0343440 VERIFIED: YES
Provenance & Taxonomy
Bacillus polymyxa [Bacterium]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Lipidation
Esterification
The carboxylic end of Ala6 forms an ester bond with the hydroxyl group of T1. Val2, Gln5, Ala6 are D-amino acids and Thr4 is a D-allo-Thr. In addition, the N-terminus NH is lipidated with 15-guanidino-3-hydroxypentadecanoic acid (GHPD). Refer to the article for additional physical properties
Bio-Activity Profile
Antimicrobial Antifungal
fungi Fusarium oxysporum HF8801, Fusarium oxysporum HF8835, A. niger HUT 2016, A. oryzae 1FO 4214, and P. thomii
1.56-3.12 μg/mL
MIC
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