Peptide Database

Peptide NameCholecystokinin-58

Function Ontology

Gastrointestinal bioactivity

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length58 amino acids

Chemical FormulaC287H461N89O83S3

DescriptionStandard

        AVQKVDGEPRAHLGALLARYIQQARKAPSGRMSVIKNLQSLDPSHRISDRDYMGWMDF
    

Molecular Weight6582.47 Da

Isoelectric Point (pI)9.81

Net Charge (pH 7.0)2.97

Net Charge (pH 7.4) 2.67

Charge Density (pH 7.0) 0.0513

GRAVY Index-0.57

Hydrophobic Moment 0.67

Boman Index-0.13

Instability Index46.04

Aliphatic Index 79.14

Aromaticity 0.0690

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2799.12

LogP -28.31

H-bond Donors 98.0

H-bond Acceptors 91.0

Rotatable Bonds 220.0

Heavy Atoms 462.0

Ring Count 10.0

Amide Bonds 62.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0067359 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyGastrin/cholecystokinin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Other ModsTyr52 Sulfotyrosine

Bio-Activity Profile

Function

Hormone Gastrointestinal Neuropeptide

RECORD: Rec_0287637 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyCholecystokinin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

C-TermAmidation

Other Mods52:Sulfotyrosine

Bio-Activity Profile

Function

-

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour