Peptide Database

Peptide NameBAFF

Function Ontology

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length285 amino acids

Chemical FormulaC1382H2229N373O425S11

DescriptionStandard

        MDDSTEREQSRLTSCLKKREEMKLKECVSILPRKESPSVRSSKDGKLLAATLLLALLSCCLTVVSFYQVAALQGDLASLRAELQGHHAEKLPAGAGAPKAGLEEAPAVTAGLKIFEPPAPGEGNSSQNSRNKRAVQGPEETVTQDCLQLIADSETPTIQKGSYTFVPWLLSFKRGSALEEKENKILVKETGYFFIYGQVLYTDKTYAMGHLIQRKKVHVFGDELSLVTLFRCIQNMPETLPNNSCYSAGIAKLEEGDELQLAIPRENAQISLDGDVTFFGALKLL
    

Molecular Weight31222.44 Da

Isoelectric Point (pI)5.92

Net Charge (pH 7.0)-3.17

Net Charge (pH 7.4) -3.78

Charge Density (pH 7.0) -0.0111

GRAVY Index-0.23

Hydrophobic Moment 0.68

Boman Index0.01

Instability Index50.45

Aliphatic Index 91.09

Aromaticity 0.0632

Extinction Coeff. Reduced 15930.00

Extinction Coeff. Oxidized 16305.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0295764 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidereported in GtoPdb PTM annotation

Other ModsN-linked glycosylation of asparagine residues at positions 124 and 242 (high mannose at 242); disulphide bond formation between cysteine residues at positions 232 and 245

Bio-Activity Profile

Function

Signaling peptide

TargetBAFF receptor (Human); B cell maturation antigen (Human); TACI (Human)

Activity0.09-0.135 nM

MethodKd